Internal tremor is a sensory symptom experienced subjectively by the patient but cannot be seen by observers. These internal tremors are relatively common, with up to 44% of patients reporting internal tremors lasting less than half an hour, but occurring several times a week. Dr. William Weiner and Dr. Lisa Shulman, experts in PD at University of Maryland conducted a retrospective study on this problem in 1996.The doctors investigated the prevalence and characteristics of internal tremor by administering a questionnaire to 100 consecutive patients with PD and 50 age-matched controls seen in their movement disorders center. A sensation of internal tremor was present in 44% of this sample of PD patients and in 6% of the control population. The frequency of other sensory symptoms (aching, tingling, burning) was higher in the PD patients with internal tremor (73%) than in those without (45%; p = 0.005). Most interestingly, they found internal tremor was associated with anxiety in 64% of patients. It was described as uncomfortable and was unrelieved by antiparkinsonian medication in three quarters of patients. A sensation of internal tremor is commonly reported by PD patients and should be recognized as a useful diagnostic factor in PD. Source:Mov Disord 11:3-7 (1996) If your sister is found to have signs and symptoms of PD, then treatment of those symptoms with anti-PD meds might help with at least the muscle aching, but will be unlikely to help other sensory complaints. Another class of medication that might help her are the anti-depressants. Finally, medications used to treat painful neuropathies such as Gabapentin (Neurontin)may help. Powerful pain killes such as Darvon should not be used as she discovered.

Thank you for your reply. My sister was unable to walk after her fall. After a week in the hospital she was placed in rehab where she has been learning to walk with the help of a walker & assistance. The anxiety connection seems relevent in her case because she no longer complains of the internal tremors and burning.Our mother, brother, and another sister all had P.D. so I believe this is her problem.